Forkhead Box O4 (FOXO4) (C-Term) Peptide
FOXO4
适用: 人, 小鼠
宿主: 合成
BP, WB
Quick Overview for Forkhead Box O4 (FOXO4) (C-Term) Peptide (ABIN977074)
抗原
FOXO4
(Forkhead Box O4 (FOXO4))
宿主
人, 小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- PPVMAGAPIP KVLGTPVLAS PTEDSSHDRM PQDLDLDMYM ENLECDMDNI
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Foxo4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FOXO4 (Forkhead Box O4 (FOXO4))
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背景
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Foxo4 is a transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. It represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin.
Alias Symbols: Afxh, MGC117660, Mllt7, afx
Protein Size: 505 -
分子量
- 54 kDa
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基因ID
- 54601
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NCBI登录号
- NM_001005872, NP_001005872
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UniProt
- Q99MK2
抗原
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